Sea12 Technologies

IT Software Services / Solutions

In 2023, a group of visionary scientists and investors recognized that drug discovery remained an expensive, time-consuming process with high failure rates. Despite advances in AI, the pharmaceutical industry was still struggling to translate computational insights into viable medicines. This realization sparked the creation of Xaira Therapeutics - co-founded and incubated by ARCH Venture Partners and Foresite Labs - to build an integrated biotechnology company that would truly harness the transformative power of artificial intelligence for drug discovery. Built on the groundbreaking protein design work of Nobel Laureate Dr. David Baker and his team at the University of Washington's Institute for Protein Design, Xaira brings together advanced AI research, expansive data generation, and robust therapeutic product development. The company emerged from stealth mode in 2024 with over $1 billion in funding, ready to revolutionize how we treat disease by making predictions about the right biology to target, the best therapeutics to modulate those targets, and the patients who will benefit most. With offices in South San Francisco, Seattle, and London, Xaira is shifting drug discovery from an empirical science to a precise engineering discipline.

Bloomreach is revolutionizing ecommerce through its AI-powered Loomi platform, which unifies real-time customer and product data to create limitless personalized shopping experiences. By understanding individual customer intent and connecting that intelligence across every channel - from email and SMS to web search and mobile apps - the company enables brands to deliver magical, memorable interactions that drive measurable business growth. Their autonomous search technology goes beyond keyword matching to truly comprehend what shoppers want, while their conversational shopping agents scale the expertise of the best sales associates to guide customers to perfect purchases instantly. Since 2009, Bloomreach has grown to power 25% of all ecommerce experiences in the US and UK, serving over 1,400 global brands including American Eagle, Pandora, and Red Bull. With 900+ employees worldwide and multiple patents for their AI/ML innovations, they process 250 million searches daily and help marketers execute 100,000 email campaigns every day. Their mission - to drive magical and measurable experiences for people and businesses - has made them the trusted Commerce Experience Cloud for retailers, brands, and B2B companies seeking to break the limits of what's possible in digital commerce.

Protogon Research builds autonomous AI systems and deploys them directly into financial markets through proprietary trading. The company's stated mission is to develop the most intelligent AI systems in the world, using trading as a practical testbed for AI that genuinely understands the world - rather than one that simply replicates human behaviour or produces superficial outputs. Its long-term research aim is to chart a path toward superintelligence. The company was founded by Rafael Cosman, a serial entrepreneur who previously co-founded Archblock and the TrueFi DeFi protocol. Protogon Research is backed by Zelda Ventures, OVO, and StartX, and is a member of the NVIDIA Inception Program. Protogon's technical work spans machine learning, AI research, trading, and operations. The company describes its technology as original, proprietary, and defensible, and positions itself deliberately apart from traditional quantitative trading firms: the priority is building lasting, transformative AI systems rather than optimising for short-term trading profits. The team is described as highly technical, with deep expertise across its core domains.

Conifers.AI is transforming security operations centers (SOCs) with CognitiveSOC™, an agentic AI platform that enables enterprises and managed security service providers to achieve SOC excellence. The company addresses a critical challenge in modern cybersecurity: SOCs are drowning in alert volumes - processing an average of 960 alerts daily, with large enterprises facing over 3,000 alerts from 30+ security tools. This overload forces security teams to make difficult trade-offs between comprehensive coverage and thorough investigation quality. CognitiveSOC™ stands apart as the industry's first mesh agentic AI platform built specifically to solve complex, multi-tier SOC challenges at scale. Unlike traditional automation tools that focus solely on basic triage, Conifers delivers comprehensive coverage across all investigation tiers with verified performance: 87% faster investigations, 3x SOC throughput, approximately 2.5-minute average investigation time, and greater than 99% accuracy. The platform combines multiple AI techniques - including large language models, domain-specific language models, machine learning, statistical analysis, and static analysis - in an intelligent orchestration layer that applies the optimal combination of capabilities to each incident. This patent-pending architecture continuously learns from organizational policies, procedures, and risk tolerances, ensuring investigations align with each customer's unique context. Founded in 2024 by security industry veterans and backed by SYN Ventures, PICUS Capital, and Washington Harbour Partners, Conifers has been recognized by Gartner as "the company to beat in AI SOC Agents for threat investigation."

Duku AI builds an autonomous testing platform designed to remove the manual burden of software quality assurance. Its platform deploys AI agents that simulate real customer journeys after every build, catching failures before users encounter them. Rather than requiring teams to write and maintain test scripts, the system self-heals as codebases evolve - eliminating the flaky tests and stale test suites that slow down engineering teams. The company is led by operators with experience scaling Meta's testing infrastructure, launching Uber's global playbooks, and growing Deliveroo from its early stages to hypergrowth. That background informs both the product's technical architecture and its positioning: giving engineering and product teams the confidence to ship quickly without sacrificing reliability. Despite being a three-person team, Duku AI has reached $330,000 in revenue in 2025. The company is venture-backed.